Born in Cesena in 1975. After getting a degree in architecture (Venice, 2000), he moved to Berlin, where he worked until 2005 as a cartoonist, illustrator and architect. In 1994 he won the first prize at “Bienal do Juvenes Criadores do Mediteraneo,” Lisbon – comics. His collaboration with the German publisher Avant-Verlag began in 2001 with the magazine Plaque, which brings together a wide range of Italian authors, among them Mattotti, Igort, and Giandelli. Since then he began an intense work on comic short stories written by his brother Daniele, which appeared in Black, Bile Noire, Stripburger, Forresten, and Osmosa. He published the graphic novels Celestia – Oblomov / Atrabile 2020, L’Ora dei Miraggi – Oblomov 2017, Les Variations D’Orsay – Futuropolis 2015, L’Entrevue – Futuropolis 2013, Cinq Mille Kilomètres Par Seconde – Atrabile 2010, Mademoiselle Else – Delcourt 2009, Icarus – Atrabile 2006, Les Gens Le Dimanche – Atrabile 2004.
He collaborates with his illustrations for The New Yorker, Le Monde, Vanity Fair, Feltrinelli, Einaudi, La Repubblica, Sole 24 Ore, Edizioni EL, Fabbri, Internazionale, Il Manifesto, Rolling Stone Magazine, Les Inrocks, Nathan, Bayard, Far East Festival.
Manuele lives in Paris.